The article deals with some issues of vaccination safety. Contraindications and precautions for vaccination are indicated. The vaccines classification, their general characteristics, the list of the vaccines used in the Republic of Belarus are presented. The vaccines and their basic reactogenic components that can cause side effects after immunization are listed. The variants, frequency, some pathogenic mechanisms of adverse reactions to the vaccines various components are presented. The patient management at the allergic reaction to a vaccine components is indicated.

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Автор(ы): A. P. Ruban