Objective. The purpose of the study was to develop ultrasound diagnostics algorithms of elevated LV filling pressure at rest.
Materials and methods. In 2017—2018, a clinical and instrumental examination of 246 patients aged 40—86 years was performed. Criteria for inclusion in the study: sinus rhythm in patients, essential arterial hypertension, chronic ischemic heart disease, previous left ventricular myocardial infarction, CHF. Transthoracic echocardiography was performed on
a Siemens Acuson S1000 ultrasound machine (Germany).
Results. The indicators sensitive and specific for elevated LV filling pressure at rest should be calculated by echocardiography in case of NT-proBNP value is more than 663 pg/ml (sensitivity 76.9%, specificity 89%). When mitral
E/e’septal >11.5 (sensitivity 93%, specificity 96%) and e’septal£6 cm/sec (sensitivity 87.7%, specificity 78.8%), LV ejection fraction £49.51% (sensitivity 86%, specificity 87%), patients with sinus rhythm without primary mitral regurgitation and mitral stenosis have an elevated LV filling pressure at rest. Auxiliary diagnostic criteria: left atrial volume index >43.3 ml/m2 (sensitivity 83%, specificity 73%), value Ardur–Adur >32 ms (sensitivity 78%, specificity 71%), DTE of peak E of transmitral blood flow £155 msec (sensitivity 96%, specificity 61%).
Conclusion. The developed algorithms and criteria for the diagnosis of elevated LV filling pressure have good indicators of sensitivity and specificity.Ключевые слова:
Автор(ы): O. M. Zherko