ULTRASOUND DIAGNOSTICS OF ELEVATED FILLING PRESSURES OF THE LEFT VENTRICLE AT REST

Objective. The purpose of the study was to develop ultrasound diagnostics algorithms of elevated LV filling pressure at rest.

Materials and methods. In 2017—2018, a clinical and instrumental examination of 246 patients aged 40—86 years was performed. Criteria for inclusion in the study: sinus rhythm in patients, essential arterial hypertension, chronic ischemic heart disease, previous left ventricular myocardial infarction, CHF. Transthoracic echocardiography was performed on
a Siemens Acuson S1000 ultrasound machine (Germany).

Results. The indicators sensitive and specific for elevated LV filling pressure at rest should be calculated by echocardiography in case of NT-proBNP value is more than 663 pg/ml (sensitivity 76.9%, specificity 89%). When mitral
E/e’septal >11.5 (sensitivity 93%, specificity 96%) and e’septal£6 cm/sec (sensitivity 87.7%, specificity 78.8%), LV ejection fraction £49.51% (sensitivity 86%, specificity 87%), patients with sinus rhythm without primary mitral regurgitation and mitral stenosis have an elevated LV filling pressure at rest. Auxiliary diagnostic criteria: left atrial volume index >43.3 ml/m2 (sensitivity 83%, specificity 73%), value Ardur–Adur >32 ms (sensitivity 78%, specificity 71%), DTE of peak E of transmitral blood flow £155 msec (sensitivity 96%, specificity 61%).

Conclusion. The developed algorithms and criteria for the diagnosis of elevated LV filling pressure have good indicators of sensitivity and specificity.

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Автор(ы): O. M. Zherko