The article presents data of the use of alpha-blockers as first-line drugs in the treatment of benign prostatic hyperplasia, assesses their effectiveness in the treatment of symptoms of the lower urinary tract, recites side effects. The results of both monotherapy and their combination with inhibitors of 5-alpha-reductase and phosphodiesterase-5 are reflected. Attention is drawn to the need to use alpha-1-blockers in the treatment of acute urinary retention, which makes it possible to restore urination twice as often and avoid urgent surgical treatment. The use of alpha-1-blockers promotes more successful independent passage of ureteral calculus up to 10 mm in size than when using a placebo.

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Автор(ы): A. V. Strotski