Objective. To compare pachymetry data received at an optical coherence tomograph (SOCT Copernicus REVO) and using a Scheimpflugkeratotopograph (TOMEY TMS-5) in healthy eyes and in eyes with keratoconus.

Materials and methods. 99 patients (174 eyes) were involved in the study. The main group included 86 patients
(148 eyes) with keratoconus and the control group consisted of 26 healthy eyes of 13 patients. In addition to a standard ophthalmological examination, all the patients underwent pachymetry using a Scheimpflugkeratotopograph (TOMEY TMS-5) and an optical coherence tomograph (SOCT Copernicus REVO).

Results. There was no statistically significant difference in the results of the corneal pachymetry performed bye two methods in the control group (p=0.62 — for the central corneal thickness (CCT) and p=0.33 — for the smallest corneal thickness (TCT)). Statistically significant difference between the methods was obtained in the main group of patients with keratoconus for both the CCT (p=0.02) and TCT (p<0.001).

Conclusion. A Scheimpflug-keratotopography (TOMEY TMS-5) and an OCT (SOCT Copernicus REVO 80) are highly accurate methods of pachymetry. Presence of significant differences in the measurements by the Scheimpflug camera pachymetry and using OCT in patients with keratoconus should be taken into account while diagnosing, performing dynamic observation, and evaluating treatment. It is recommended to compare the data changes obtained by the same device for the disease appropriate monitoring.