DETERMINATION OF VIRAL HEPATITIS B, C AND HIV-INFECTION MARKERS AMONG MEDICAL WORKERS. REPORT 1. EPIDEMIOLOGY

Objective. Determine the prevalence of parenteral hepatitis B, C and HIV among medical workers and support staff in the Republic of Belarus.

Materials and methods. The study included 2,427 serum/plasma samples collected from medical patients from all regions of the country. All samples were examined by ELISA and PCR for presence of infections markers.

Results. The occurrence of parenteral hepatitis B, C and HIV among medical workers of different specialties was determined. As a result of the studies, markers of hepatitis B virus (HBsAg) were detected in 276 patients (11.4%), antibodies to hepatitis C virus were detected in 357 (14.7%) subjects and HIV – in 32 (1.3%) persons. In 1762 (72.6%) serum / plasma samples virus markers were not detected. 102 samples of HBV DNA, 43 samples of hepatitis C virus were sequenced. None of the serum / plasma samples positive for HIV markers could be sequenced.

Conclusion. Most often, markers of HBV, HCV and HIV were detected in nurses. Thus, markers of hepatitis C virus were identified in 151 (42.3%) of 357 cases, hepatitis B virus in 135 (48.9%) of 276 cases and HIV markers in 15 (46.9%) of 32 positive samples.

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Автор(ы): V. F. Eremin, E. L. Gasich, M. G. Tulinova, N. D. Kolomiets