EXPERIENCE OF MANAGING PREGNANT WOMEN WITH LYMPHOMAS

Objective. To analyze the possibility of prolonging pregnancy among women with lymphomas.

Materials and methods. We studied the course of pregnancy and childbirth among women with lymphomas, and analyzed the impact of pregnancy on the prognosis and outcomes of lymphomas. We examined 133 patients with pregnancy-associated lymphomas and a control group — 133 patients with non-pregnancy lymphomas. A method for lymphomas managing in pregnant women not interrupting the same and not worsening the disease prognosis was elaborated.

Results. The 5-year overall survival rate in the main group of patients with lymphomas was 98.5±1.1%, and the 10-year survival rate was 96.6±2.1%. For the control group of patients with lymphomas, the 5-year overall survival made 96.7±1.6%, and the 10-year survival – 95.4±2.1%. There was no difference in the overall survival between the compared groups (р>0.05). For the control group, the 5-year event-free survival was 83.3±3.4, 10-year 81±3.7; for the main group – 97.7±1.3, 10-year – 94.6±2.2, respectively. Thus, in the main group the follow-up period being longer, statistically significantly better survival rates were observed (p<0.05). If necessary, radiation therapy was performed in the postpartum period.

Conclusion. The comparative analysis of the long-term treatment results did not reveal statistically significant differences in the main and control groups.

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Автор(ы): N. L. Andreyeva