Objective. to study the socio-economic significance of mortality from external causes.

Materials and methods. Based on the data of the National Statistical Committee of the Republic of Belarus, the number of residents of the republic who did not reach working age was calculated, information was analyzed on the value of the produced gross domestic product and the number of employed population from 2015 to 2019. Based on the information received, the DALY value was calculated.

Results. Under 40 years, the leading cause of death of the population is external causes; after 40 years, there is
a traditional structure of mortality рopulation — the predominance of cardiovascular and oncological pathology. The losses of society caused by mortality from external causes under 40 years are almost 5 times higher than the losses caused by mortality from cardiovascular pathology and 3 times from cancer.

Conclusions.  Using of the DALY methodology shows that the greatest economic losses of the state in working age are due to mortality from external causes.

Mortality from external causes prevails under the age of 40, the leading causes of death from external causes are suicide and alcohol poisoning.

At the age of over 40, mortality from cardiovascular and oncological pathology prevails, and then mortality from external causes follow.