The article provides evidence of the possibility of using linear regression of systolic pressure on pulse pressure in the individual series of blood pressure (BP) values for determining the hemodynamic phenotype basing on the quantitative values of individual regression coefficients. The basic principles of the functional systems theory and of the physiological hemodynamic laws as well as modern mathematical methods of analysis were used. Examples of other computational models built exactly on linear relationships between the BP parameters are given and show practical benefits for clinical medicine. The BP parameters hemodynamics in the harmonic phenotype has been proved to be weakly non-linear, therefore, it can be described adequately by the linear regression and be used for a further linear analysis. However, it is significantly non-linear in the dysfunctional phenotypes limiting the possibilities of further linear modeling in these phenotypes by certain conditions. The method proposed for determining the hemodynamic phenotype can be useful in medical practice for revealing clinically latent circulatory disorders and latent hypertension in normotensive people and personalizing treatment in patients with hypertension taking into account the phenotype.