A morpho-histological study of small laboratory animals (rats) tissues after perforated and non-perforated titanium implants was undertaken to demonstrate the accuracy of the theoretical preconditions for creating a combined implant for the elimination of orbital bone defects in practice.

180 rats involved in the research and divided into 3 groups. The first group were implanted with non-perforated plates. The second group had perforated plates, еhe third group had snail-type implants. The necessity to create a titanium implantation plate with combined properties of perforated and non-perforated material was proven.