EFFECT OF MICRO-PULSE TRANSSCLERAL CYCLOPHOTOCOAGULATION ON CORNEAL ENDOTHELIUM

Objective. To evaluate the micropulse transscleral cyclophotocoagulation effect on the corneal endothelium, namely on the endothelial cell density (ECD) and the percentage of hexagonal cells (HEX).

Materials and methods. A prospective study including 21 patients (34 eyes) with primary open-angle and pseudoexfoliative glaucoma stage 1—3 treated with microimpulse transscleralcy clophotocoagulation was performed. At different periods of observation, the density of endothelial cells and the HEX percentage in the central zone of the cornea were measured.The observation period was 12 months.

Results. The differences between the CD values before the surgery (Me 2471) and after 12 months (Me 2446) were not statistically significant (p = 0.105).A statistically significant (p = 0.0001) increase in the HEX percentage was found: before the surgery — Me 49.5 and after 12 months — Me 52.

Conclusion.The micro-pulse transscleral cyclophotocoagulation does not cause a statistically significant decrease in the ECD values. After the treatment, the HEX percentage increase reliably as compared to the levels of the cells of other types. The method has no negative effect on the corneal endothelium.

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Автор(ы): E. V. Miloshevsky, T. A. Imshanetskaya