ANTIBODIES TO KU-ANTIGEN IN PATIENTS WITH SYSTEMIC CONNECTIVE TISSUE DISEASES

The article presents literature data on the history of anti-Ku antibodies’ discovery, their clinical significance, frequency of occurrence in systemic connective tissue diseases. The clinical manifestations of the main diseases associated with anti-Ku antibodies are described. Two clinical cases of patients with systemic connective tissue diseases associated with isolated increase of antibodies in the blood are presented. In the first case idiopathic polymyositis with systemic sclerosis is discussed. In the second case systemic sclerosis with erosive polyarthritis is presented.

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Автор(ы): N. F. Soroka, I. P. Grigortchouk, O. P. Sirosh