As studies of recent years show each patient who underwent surgery has the adhesion process of the abdominal cavity to one degree or another. The consequences of surgical operations remain with the patient, reminding of themselves with frequent episodes of intestinal obstruction and a significant decrease in the quality of life. Continuous discussion of options for diagnosis, treatment and, most importantly, prevention of this disease indicates about pendency of this problem. In the surgical treatment of patients with adhesive disease of the abdominal cavity and adhesive intestinal obstruction we have developed the following strategy: in the postoperative period extracorporeal detoxification with available means is indicated for treatment of intestinal obstruction with signs of peritonitis, as well as multiple organ failure. To reduce mortality and the period of stay in the intensive care unit in patients with acute adhesive intestinal obstruction it is reasonably to use goal-oriented infusion therapy, which involves the administration of small doses of inotropic agents against the background of limited volumes of infusion therapy. The use of non-steroidal anti-inflammatory drugs is an important part of pain relief. Refusal of the administration of anticoagulants in the early postoperative period creates a prerequisite for thromboembolism, as this a single administration of anticoagulants before surgery is not enough to prevent thrombosis.